庞少臣 博士

发布者:王珺发布时间:2023-03-29浏览次数:1611

姓名:庞少臣

学位:博士

职称:副研究员

电子邮箱:pangshaochen@163.com


个人照片:


研究方向

环境污染物发育毒性效应及机制

高通量毒性评价方法开发

纳米材料生物学效应

近年来围绕四溴双酚A造血发育毒性效应及毒性机制和纳米材料医用安全性评价新方法开发开展了研究工作。未来将利用斑马鱼和细胞模型开发造血发育毒性高通量识别方法,包括方法开发与验证、设备组装与搭建、自动化数据处理方法开发;有机污染物造血发育毒性的高通量筛查等。

教育经历

2004/09-2008/7,武汉理工大学,生物技术,学士

2008/09-2014/7,中国科学院水生生物研究所,遗传学,博士

2016/06-2020/12,中国科学院生态环境研究中心,环境化学,博士后

主持或参加科研项目

  1. 国家自然科学基金面上项目,22276074,“农药造血发育毒性高通量识别方法及毒性机制研究”,2023.01-2026.1254万元,主持

  2. 国家自然科学青年基金项目,21707050纳米银对斑马鱼尾鳍伤口愈合和组织再生的抑制效应及分子机制研究2018/01-2020/1225万元,结题,主持

  3. 中国博士后科学基金,2016M601147,基于斑马鱼原始生殖细胞的环境污染物生殖毒性研究,2016-20175万元,结题,主持

代表性论著

  1. Pang, S.; Gao, Y.; Wang, Y.; Yao, X.; Cao, M.; Liang, Y.; Song, M.*; Jiang, G., Tetrabromobisphenol A perturbs cell fate decisions via BMP signaling in the early embryonic development of zebrafish. Journal of hazardous materials 2022, 430, 128512.

  2. Gao, Y.; Li, A.; Zhang, W.; Pang, S.*; Liang, Y.; Song, M.*, Assessing the toxicity of bisphenol A and its six alternatives on zebrafish embryo/larvae. Aquatic Toxicology 2022, 246, 106154.

  3. Pang, S.; Gao, Y.; Li, A.; Yao, X.; Qu, G.; Hu, L.; Liang, Y.; Song*, M.; Jiang, G., Tetrabromobisphenol A Perturbs Erythropoiesis and Impairs Blood Circulation in Zebrafish Embryos. Environmental Science & Technology 2020, 54, (20), 12998-13007.

  4. Pang, S.; Gao, Y.; Wang, F.; Wang, Y.; Cao, M.; Zhang, W.; Liang, Y.; Song, M.*; Jiang, G., Toxicity of silver nanoparticles on wound healing: A case study of zebrafish fin regeneration model. Science of The Total Environment 2020, 717, 137178.

  5. Shaochen Pang, Hopeng Wang, Zuoyan Zhu and Yonghua Sun*. Transcriptional Activity and DNA Methylation Dynamics of the Gal4/UAS System in Zebrafish. Marine Biotechnology, 2015, 17(5):593-603.

  6. Shaochen Pang, Houpeng Wang, Kuoyu Li, Zuoyan Zhu, Jingxuan Kang and Yonghua Sun*. Double Transgenesis of Humanized fat1 and fat2 Genes Promotes Omega-3 Polyunsaturated Fatty Acids Synthesis in a Zebrafish Model. Marine Biotechnology. 2014, 16(5): 580-593.

  7. Minjie Chen, Jie Zhang, Shaochen Pang, Chang Wang, Ling Wang, Yonghua Sun, Maoyong Song, Yong Liang*. Evaluating estrogenic and anti-estrogenic effect of endocrine disrupting chemicals (EDCs) by zebrafish (Danio rerio) embryo-based vitellogenin 1 (vtg1) mRNA expression. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 204, 45-50, (2018).

  8. Liu, Y., C. F. Bourgeois, Shaochen Pang, M. Kudla, N. Dreumont, L. Kister, Yonghua Sun, J. Stevenin and D. J. Elliott*. The Germ Cell Nuclear Proteins hnRNP G-T and RBMY Activate a Testis-Specific Exon. PLoS Genetics, 2009, 5(11): e1000707.

  9. 孙永华,庞少臣,王厚鹏,朱作言,康景轩,一种提高鱼类omega-3多不饱和脂肪酸的方法及应用,2014.07.02,中国,CN103898159A