曹梦西,江汉大学,环境与健康研究院,副研究员
caomx@jhun.edu.cn,18971602572
研究方向:
重金属污染物的生物过程及生物修复;持久性有毒污染物的环境毒理效应
教育经历:
2010-09至2014-07,中国科学院水生生物研究所,遗传学,博士,导师:胡炜
2006-09至2009-07,华中师范大学,发育生物学,硕士,导师:赵浩斌
2002-09至2006-07,太原师范学院,生物科学,学士,导师:高晋华
科研与学术工作经历:
2020-10至现在,江汉大学,环境与健康研究院,副研究员;
2016-6至2020-12,中国科学院生态环境研究中心,环境化学与生态毒理学国家重点实验室,博士后,合作导师:史建波;
2015-11至2020-09,江汉大学,环境与健康研究院,助理研究员;
2014/07-2015/10,中国科学院水生生物研究所,淡水生态与生物技术国家重点实验室,研究助理;
2009/07-2010/08,中国科学院水生生物研究所,淡水生态与生物技术国家重点实验室,研究助理;
主持或参加科研项目(课题)情况(按时间倒序排序):
1. 科技部,国家重点研发计划合成生物学重点专项子任务,2020YFA0907404-4,“智能感知修复生物体系的生物安全性防控”,2020-11至2025-10,48万元,在研,主持。
2. 国家自然科学基金委员会,国家自然科学基金青年项目,21607059,“肠道微生物对鱼体内甲基汞去甲基化的影响”,2017-01至2019-12,20万元,已结题,主持。
3. 中国博士后科学基金会,面上资助项目,2016M601146,“渤海湾鱼体及环境中微生物与汞形态转化之间的关系”,2017-01至2018-06,5万元,已结题,主持。
4. 国家自然科学基金委员会,国家自然科学基金青年项目,21707050,“纳米银对斑马鱼尾鳍伤口愈合和组织再生的抑制效应及分子机制研究”,2018-01至2020-12,25万元,已结题,参与。
代表性研究成果和学术奖励情况
Cao Mengxi#, Wei Jinbo#, Pan Yu, Wang Ling, Li Zhunjie, Hu Yeli, Liang Yong, Cao Huiming*. Antagonistic mechanisms of bisphenol analogues on the estrogen receptor α in zebrafish embryos: Experimental and computational studies. Science of the Total Environment, 2023, 857:159259.
魏锦博,何正宇,户业丽,汪畅,王昌泽,曹慧明,曹梦西*,梁勇. 双酚A类似物的生殖毒性及人体生殖健康风险研究进展. 生态毒理学报. 2022, DOI: 10. 7524/AJE. 1673-5897.20220123002
陈路锋,潘钰,曹梦西*,张星,王璞,梁勇,蔡勇. 武汉城市湖泊表层底泥汞分布、风险评价及影响因素. 地球与环境. 2021, DOI: 10.14050/j.cnki.1672-9250.2022.50.050
何正宇, 魏锦博, 程波, 陈路锋*, 曹梦西, 阴永光, 梁勇, 蔡勇. 地表环境汞污染的生物修复技术及展望. 地球与环境. 2022, 50:415-425.
Guo Rui*, Cao Mengxi*, Hu Ming, Deng Wenchao, Zhang Wenjuan, Gao Yangguang, Ye Shihan, Zhou Weixiang, Shi Jianbo. Synthesis and toxicity of halogenated bisphenol monosubstituted-ethers: establishing a library for potential environmental transformation products of emerging contaminant. Chemistry & Biodiversity, 2020, 17(11): e2000481.
Cao Mengxi#, Song Fei#, Yang Xue, Peng Lei, Cheng Yang, Zheng Qi, Liang Yong, Wang Chang*. Identification of potential long noncoding RNA biomarker of mercury compounds in zebrafish embryos. Chemical Research in Toxicology, 2019, 32(5):878-886.
Chen Ji#, Cao Mengxi#, Zhang Aidi, Shi Mijuan, Tao Binbin, Li Yongming, Wang Yaping, Zhu Zuoyan, Trudeau Vance L, Hu Wei*. Growth Hormone Overexpression Disrupts Reproductive Status Through Actions on Leptin. Frontiers in Endocrinology, 2018, 9:131.
Cao Mengxi, Chen Ji, Peng Wei, Wang Yaping, Liao Lanjie, Li Yongming, Trudeau Vance, Zhu Zuoyan, Hu Wei*. Effects of growth hormone over-expression on reproduction in the common carp Cyprinus carpio L.. General and Comparative Endocrinology, 2014, 195:47-57.
Cao Mengxi, Yang Yuhui, Xu Hongyan, Duan Jundan, Cheng Nana, Wang Jialin, Hu Wei*, Zhao Haobin*. Germ cell specific expression of Vasa in rare minnow, Gobiocypris rarus. Comparative Biochemistry and Physiology - Part A, 2012, 162: 163-170.
Cao Mengxi, Duan Jundan, Cheng Nana, Zhong Xueping, Wang Zequn, Hu Wei*, Zhao Haobin*. Sexually dimorphic and ontogenetic expression of dmrt1, cyp19a1a and cyp19a1b in Gobiocypris rarus. Comparative Biochemistry and Physiology - Part A. 2012, 162, 303-309.
Chen Lufeng#, Zhan Xing#, Cao Mengxi, Pan Yu, Xiao Cailing, Wang Pu, Liang Yong, Liu Guangliang, Cai Yong*. Release of legacy mercury and effect of aquaculture on mercury biogeochemical cycling in highly polluted Ya-Er Lake, China. Chemosphere. 2021, 275:130011.
Cao Huiming, Wang Ling, Cao Mengxi, Ye Tong, Sun Yuzhen*. Computational insights on agonist and antagonist mechanisms of estrogen receptor α induced by bisphenol A analogues. Environmental Pollution. 2019, 248, 536-545.
Liu Chengbin, Qu Guangbo, Cao Mengxi, Liang Yong. Hu Ligang, Shi Jianbo*, Cai Yong, Jiang Guibin. Distinct toxicological characteristics and mechanisms of Hg2+ and MeHg in Tetrahymena under low concentration exposure. Aquatic Toxicology. 2017, 193, 152-159.
Peng Wei, Cao Mengxi, Chen Ji, Li Yongming, Wang Yaping, Zhu Zuoyan, Hu Wei*. GnIH plays a negative role in regulating GtH expression in the common carp, Cyprinus carpio L. General and Comparative Endocrinology. 2016, 235, 18-28
Garcia-Reyero Natàlia*, Tingaud-Sequeira Angèle, Cao Mengxi, Zhu Zuoyan, Perkins Edward, Hu Wei. Endocrinology: advances through omics and related technologies. General and Comparative Endocrinology. 2014, 203, 232-273.
Chen Ji, Cui Xiaojuan, Jia Shaoting, Luo Daji, Cao Mengxi, Zhang Yunsheng, Hu Hongling, Huang Kaiyao, Zhu Zuoyan, Hu Wei*. Disruption of dmc1 produces abnormal sperm in Medaka (Oryzias latipes). Scientific Reports. 2016, 6, 30912.
Luo Daji, Liu Yun, Chen Ji, Xia Xiaoqin, Cao Mengxi, Cheng Bin, Wang Xuejuan, Gong Wuming, Qiu Chao, Zhang Y, Cheng Christopher, Zhu Zuoyan, Hu Wei*. Direct production of XYDMY- sex reversal female medaka (Oryzias latipes) by embryo microinjection of TALENs. Scientific Reports. 2016, 5, 14057.
俞薇,曹梦西,陈戟,贾少婷,李勇明,朱作言,胡炜*. 鲤性腺GnRH-GtH旁分泌系统的发现及其在生长/生殖调控中的作用. 农业生物技术学报. 2017, 25 (9) :1516-1525
曹梦西,杨玉慧,江文波,王玉凤,胡炜,赵浩斌*. 稀有鮈鲫脑芳香化酶cDNA片段的克隆与表达分析. 水生生物学报. 2009, 33(4): 748-755.
刁星,曹梦西,刘广良,梁勇,“一种用于痕量汞分析的反应釜及汞捕集结构”,2017-12-08,中国,ZL 201721700442.2.
梁勇,陈博磊,曹梦西,王璞,王慧敏,毕永红,“一种悬浮种植生长装置”2021-12-08,中国,ZL 202121393130.8